University of Tartu, Estonia

DNA origami-directed liposome biohybrid assemblies

In this project we will apply DNA:RNA origami and liposome technologies in programmable hybrid liposome assemblies and vesicular architectures that can be further adjusted for biomedical and bioengineering applications, including biocatalytic control, disease-specific drug delivery, or tissue-specific gene transfer. The expected results include the formation of DNA origami-modulated liposomal building blocks and the channelling of cargo materials between liposomal containers or between liposomes and cells using molecular gating systems. 

Prof. Veikko Linko

Principal Investigator

Shihab Ud Dowla

Doctoral candidate

Planned Secondments

Technical University Dortmund

Prof. Amelie Heuer-Jungemann Lab, Hybrid Bionanosystems

SISSA Trieste

Prof. Cristian Micheletti Group, Molecular and Statistical Biophysics