Hybrid Sensing in the Bionano-Systems: Imaging, Biosensing and Interaction

In this work package, we will expand the possibilities of self-assembled hybrid nanostructures in combination with single-molecule techniques for nanoscale revelation of biomolecular mechanisms, for screening applications of molecular binders, enhanced imaging schemes and signal amplification.

Meet the research teams

RNA-producing antimicrobial synthetic cells made from nucleic acid:enzyme hybrids

University of Cambridge

Local PAINT superresolution microscopy for multiplexed RNA detection

LMU Munich

Predictive modelling of translocation properties of nucleic acids and protein assemblies

SISSA Trieste

Mechanics of DNA–RNA Hybrids and Their Interaction with Proteins

CSIC Madrid

Functional proteins combined with DNA-Origami assisted fluorescence enhancement for next generation sequencing

GATTAquant

Decoding and Engineering Immunological Synapses: Super-Resolution Mapping and Patterned Therapeutics

LMU Munich