BioHYBRITE aims at enabling technological advances through the integration of bottom-up molecular molecular with top-down conventional nanotechnology, innovatively combining DNA:RNA and protein nanotechnology. A total of fifteen Doctoral Candidates will be trained on a unique mix of experimental and computational skills at the emerging nanobiotechnological interface with direct access to application ad industrial partners. Here you can find our research projects:
- Local PAINT superresolution microscopy for multiplexed RNA detection
Tinnefeld lab, LMU Munich, Germany more… - Decoding and Engineering Immunological Synapses: Super-Resolution Mapping and Patterned Therapeutics
Jungmann lab, LMU Munich/MPI of Biochemistry, Germany more… - Computational de novo protein design of specific NA-binders
Khmelinskaia lab, LMU Munich, Germany more… - DNA and RNA strand displacement in complex environments
Simmel lab, TU Munich, Germany more… - Probing silicification as a means to achieve impermeable or selectively permeable DNA origami cages for biocatalysis Heuer-Jungemann lab, TU Dortmund, Germany more…
- Nanopore screening of nucleic acid:protein hybrids for antibacterial functions
Keyser lab /Mela lab, University of Cambridge, UK more… - RNA-producing antimicrobial synthetic cells made from nucleic acid:enzyme hybrids
Di Michele lab, University of Cambridge, UK more… - Designing programmable biohybrid molecular machines
Margeat/Bellot lab, Centre de Biologie Structurale, Montpellier, France more… - Mechanics of DNA–RNA Hybrids and Their Interaction with Proteins
Moreno-Herrero lab, CNB-CSIC Madrid, Spain more… - DNA-protein hybrids for tracking and sensing biochemical cues
Ricci lab, University of Tore Vergata Rome, Italy more… - Intelligent design of artificial nucleic acid sequences (aptamers) for sensing
Garoli lab, University of Modena and Reggio Emilia, Italy more… - Predictive modelling of translocation properties of nucleic acids and protein assemblies
Micheletti lab, SISSA Trieste, Italy more… - DNA origami-directed liposome biohybrid assemblies (Linko Lab, University of Tartu, Estonia) more…
- Predictive modelling for nucleic acid strand displacement in hybrid settings
Ouldridge lab, Imperial College London, UK more… - Functional proteins combined with DNA-Origami assisted fluorescence enhancement for next generation sequencing GATTAquant & LMU Munich, Germany more…